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Home Antibody All anti-NPHS1 antibodies

Anti-NPHS1 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319690
  • Rabbit Polyclonal Nephrin Antibody
100ug 325 3-7 Days
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IHC(1)

OriGene Data

ImmunogenNephrin antibody was raised against a 16 amino acid synthetic peptide from near the center of human Nephrin.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *IHC Suggested DilutionsELISA, IHC: 5 ug/ml
BufferNephrin Antibody is supplied in PBS containing 0.02% sodium azide.
Purification Nephrin Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens nephrosis 1, congenital, Finnish type (nephrin) (NPHS1)
Alternative NameCNF; nephrin; NPHN
Database LinkNP_004637
Entrez Gene 4868 Human
FunctionNephrin Antibody: Nephrin is strongly expressed in renal glomeruli and is a member of the immunoglobulin family of cell adhesion molecules. Mutations in the Nephrin gene result in congenital nephrotic syndrome, an autosomal-recessive disorder characterized by massive proteinuria in utero and nephrosis at birth. Renal glomeruli allow normal kidneys to filter plasma so that it is very pure. Nephrin is expressed in the podocyte slit-diaphragm of the renal glomeruli in a manner that suggests that Nephrin molecules homodimerize in an anti-parallel fashion similar to cadherin interactions in adherens junctions. Thus, Nephrin may constitute the entire extracellular structure of the slit-diaphragm.
Related PathwayTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

IHC Image
Immunohistochemistry of Nephrin in human kidney tissue with Nephrin antibody at 5 ug/mL.

 

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