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Anti-NLRX1 Antibody Polyclonal
Also for NLRX1 (NM_024618)
|NOD5 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human NOD5.|
|Human, Mouse, Rat
||ELISA, WB: 1 - 2 ug/ml, IHC: 10 ug/ml, IF: 20 ug/ml
|NOD5 Antibody is supplied in PBS containing 0.02% sodium azide.|
|NOD5 Antibody is affinity chromatography purified via peptide column. (Protein A or G Sepharose)
|Homo sapiens NLR family member X1 (NLRX1), transcript variant 1|
|CLR11.3; DLNB26; NOD26; NOD5; NOD9|
|NOD5 Antibody: NOD5, also known as NLRX1, is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD5 localizes to the mitochondrial outer membrane and interacts with the virus-induced signaling adapter protein VISA. Unlike a subset of NOD-like receptors (NLRs) such as NOD1 and NOD2 which trigger pro-inflammatory cascades, and other NLRs that induce the caspase 1 inflammasome in response to immune challenges, NOD5 amplifies NF-κB and JNK pathways by inducing reactive oxygen species production.|
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Western blot analysis of NOD5 in rat spleen tissue cell lysate with NOD5 antibody at (A) 1 and (B) 2 ug/mL.
Immunohistochemistry of NOD5 in rat spleen tissue with NOD5 antibody at 10 ug/mL.