Home Antibody All anti-NLRP5 antibodies
Anti-NLRP5 Antibody Polyclonal
Also for NLRP5 (NM_153447)
|NALP5 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human NALP5.|
|Human, Mouse, Rat
|WB, IHC, IF
||WB: 1 ug/ml, IHC: 10 ug/ml, IF: 20 ug/ml
|NALP5 Antibody is supplied in PBS containing 0.02% sodium azide.|
|NALP5 Antibody is affinity chromatography purified via peptide column.
|Homo sapiens NLR family, pyrin domain containing 5 (NLRP5)|
|CLR19.8; MATER; NALP5; PAN11; PYPAF8|
|NALP5 Antibody: NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP5, also known as MATER, is a maternal gene required for early embryonic development in mice. Increased NALP5 expression was observed in two neuronal injury models, and transient expression of recombinant NALP5 in neurons induced caspase-3 activation and apoptosis, suggesting that NALP5 also plays a role in caspase activation and apoptosis in injured neurons, and may thus represent a novel target for therapeutic treatment in neurodegenerative disorders.|
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Western blot analysis of NALP5 in mouse brain tissue lysate with NALP5 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
Immunohistochemistry of NALP5 in human brain tissue with NALP5 antibody at 10 ug/mL.
Immunofluorescence of NALP5 in human brain tissue with NALP5 antibody at 20 ug/mL.