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Home Antibody All anti-NLRP5 antibodies

Anti-NLRP5 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA320093
  • Rabbit Polyclonal NALP5 Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC403509) , 20ug
100ug 325 3-7 Days
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WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenNALP5 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human NALP5.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 ug/ml, IHC: 10 ug/ml, IF: 20 ug/ml
BufferNALP5 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification NALP5 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens NLR family, pyrin domain containing 5 (NLRP5)
Alternative NameCLR19.8; MATER; NALP5; PAN11; PYPAF8
Database LinkNP_703148
FunctionNALP5 Antibody: NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP5, also known as MATER, is a maternal gene required for early embryonic development in mice. Increased NALP5 expression was observed in two neuronal injury models, and transient expression of recombinant NALP5 in neurons induced caspase-3 activation and apoptosis, suggesting that NALP5 also plays a role in caspase activation and apoptosis in injured neurons, and may thus represent a novel target for therapeutic treatment in neurodegenerative disorders.
Related Pathway

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WB Image
Western blot analysis of NALP5 in mouse brain tissue lysate with NALP5 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
IHC Image
Immunohistochemistry of NALP5 in human brain tissue with NALP5 antibody at 10 ug/mL.
IF Image
Immunofluorescence of NALP5 in human brain tissue with NALP5 antibody at 20 ug/mL.

 

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