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Home Antibody All anti-NLRP5 antibodies

Anti-NLRP5 Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA320093 Rabbit Polyclonal NALP5 Antibody 100ug $325 3 Weeks
LC403509 NLRP5 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenNALP5 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human NALP5.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 ug/mL, ICC: 10 ug/mL, IF: 20 ug/mL
BufferNALP5 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification NALP5 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens NLR family, pyrin domain containing 5 (NLRP5)
Alternative NameCLR19.8; MATER; NALP5; PAN11; PYPAF8
Database LinkNP_703148
Entrez Gene 126206 Human
Entrez Gene 23968 Mouse
Entrez Gene 308325 Rat
FunctionNALP5 Antibody: NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP5, also known as MATER, is a maternal gene required for early embryonic development in mice. Increased NALP5 expression was observed in two neuronal injury models, and transient expression of recombinant NALP5 in neurons induced caspase-3 activation and apoptosis, suggesting that NALP5 also plays a role in caspase activation and apoptosis in injured neurons, and may thus represent a novel target for therapeutic treatment in neurodegenerative disorders.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of NALP5 in mouse brain tissue lysate with NALP5 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.

IHC Image
Immunohistochemistry of NALP5 in human brain tissue with NALP5 antibody at 10 ug/mL.

IF Image
Immunofluorescence of NALP5 in human brain tissue with NALP5 antibody at 20 ug/mL.


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