Home Antibody All anti-NLRP10 antibodies
Anti-NLRP10 Antibody Polyclonal
Also for NLRP10 (NM_176821)
|NALP10 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human NALP10.|
||ELISA, WB: 1 ug/ml, IHC: 10 ug/ml, IF: 20 ug/ml
|NALP10 Antibody is supplied in PBS containing 0.02% sodium azide.|
|NALP10 Antibody is affinity chromatography purified via peptide column. (Protein A or G Sepharose)
|Homo sapiens NLR family, pyrin domain containing 10 (NLRP10)|
|CLR11.1; NALP10; NOD8; PAN5; PYNOD|
|NALP10 Antibody: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP10 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It was initially identified as PYNOD, an Apaf-1-like protein that binds to ASC, caspase-1 and IL-1β, inhibiting the autoprocessing of caspase-1, caspase-1-mediated IL-1β processing, and ASC aggregation. NALP10 is thus a potent regulator of apoptosis and inflammation.|
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Western blot analysis of NALP10 in human brain tissue lysate with NALP10 antibody at 1 ug/mL.
Immunohistochemistry of NALP10 in human brain tissue with NALP10 antibody at 10 ug/mL.