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Home Antibody All anti-NLRC3 antibodies

Anti-NLRC3 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA320135
  • Rabbit Polyclonal NOD3 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC405859) , 20ug
100ug 325 3-7 Days
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WB(1)
IF(1)

OriGene Data

ImmunogenNOD3 antibody was raised against an 18 amino acid synthetic peptide near the center of human NOD3.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1 - 2 ug/ml, IF: 20 ug/ml
BufferNOD3 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification NOD3 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens NLR family, CARD domain containing 3 (NLRC3), transcript variant 1
Alternative NameCLR16.2; NOD3
Database LinkNP_849172
FunctionNOD3 Antibody: NOD3 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD3 also known as NLR family CARD containing 3 (NLRC3), is predominantly expressed in the immune system, particularly in T lymphocytes, and its expression is strongly down-regulated following stimulation of the T-cell receptor complex and CD28, suggesting that NOD3 plays a role in attenuating the activation of T cells. NOD3 inhibits NF-kappaB, AP-1 and NFAT transcriptional activation in Jurkat T cells downstream of CD3/CD28 stimulation or treatment with PMA/ionomycin and decreases IL-2 and CD25 mRNA induction in activated cells.
Related Pathway

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WB Image
Western blot analysis of NOD3 in 3T3 cell lysate with NOD3 antibody at (A) 1 and (B) 2 ug/mL.
IF Image
Immunofluorescence of NOD3 in Jurkat cells with NOD3 antibody at 20 ug/mL.

 

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