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Home Antibody All anti-NEUROG3 antibodies

Anti-NEUROG3 TRUEMAB Antibody Clone OTI5A8

TrueMAB™ Antibodies - Made against Authentic Protein Antigens


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA500090 anti-Ngn3 (Neurogenin3) mouse monoclonal antibody, clone OTI5A8 (formerly 5A8) 100ul 325
In Stock
LC402827 NEUROG3 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF500090 Carrier-free (BSA/glycerol-free) Ngn3 mouse monoclonal antibody, clone OTI5A8 (formerly 5A8) 100ug $450 3-4 weeks
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Also for NEUROG3 (NM_020999)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenRecombinant fragment expressed in E.coli corresponding to amino acids 1-214of human Ngn3
Clone NameClone OTI5A8 IsotypeIgG2b
Species ReactivityHuman Concentration0.5 mg/ml
Guaranteed Application *WB, IHC, IP Suggested DilutionsWB: 1:500, IHC: 1:150
Predicted MW Explanation 22.9 kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Reference Data

Target NameHomo sapiens neurogenin 3 (NEUROG3)
Alternative NameAtoh5; bHLHa7; Math4B; NGN-3; ngn3
Database LinkNP_066279
Entrez Gene 50674 Human
FunctionNeurogenin-3 (NEUROG3) is expressed in endocrine progenitor cells and is required for endocrine cell development in the pancreas and intestine (Wang et al., 2006 [PubMed 16855267]). It belongs to a family of basic helix-loop-helix transcription factors involved in the determination of neural precursor cells in the neuroectoderm (Gradwohl et al., 2000 [PubMed 10677506]).[
Related PathwayES Cell Differentiation/IPS Maturity onset diabetes of the young

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* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NEUROG3(RC224767) (RC224767, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NEUROG3.
Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-NEUROG3 mouse monoclonal antibody (TA500090) at 1:150 dilution at 1:150 dilution.
Immunoprecipitation of NEUROG3 by using TrueMab monoclonal anti-NEUROG3 antibody (Negative control: IP without adding anti-NEUROG3 antibody). For each experiment, 500ul of DDK tagged NEUROG3 overexpression lysates (at 1:5 dilution with HEK293T lysate), 2u


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