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Home Antibody All anti-NEU1 antibodies

Anti-NEU1 TRUEMAB Antibody Clone OTI3B8

TrueMAB™ Antibodies - Made against Authentic Protein Antigens


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA801671 NEU1 mouse monoclonal antibody, clone OTI3B8 (formerly 3B8) 100ul 325
In Stock
LC424720 NEU1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF801671 Carrier-free (BSA/glycerol-free) NEU1 mouse monoclonal antibody, clone OTI3B8 (formerly 3B8) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 48-315 of human NEU1 (NP_000425)produced in E.coli.
Clone NameClone OTI3B8 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB Suggested Dilutions WB 1:2000,
Predicted MW Explanation 40.2 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens sialidase 1 (lysosomal sialidase) (NEU1)
Alternative NameNANH; NEU; SIAL1
Database LinkNP_000425
Entrez Gene 4758 Human
FunctionThe protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity. [provided by RefSeq, Jul 2008].
Related PathwayTransmembraneDruggable Genome Other glycan degradationSphingolipid metabolismLysosome

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WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NEU1 (RC200386, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NEU1.


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