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Home Antibody All anti-NETO2 antibodies

Anti-NETO2 Antibody EPR3497

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SKU Description Amount Price Availability*  
TA307865
  • Rabbit monoclonal antibody against NETO2(clone EPR3497)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC413317) , 20ug Explanation
100ul $325 3-7 Days
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WB(2)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human NETO2 was used as an immunogen.
Clone NameEPR3497 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100
Predicted MW Explanation 60 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC or IHC-P.

Reference Data

Target NameHomo sapiens neuropilin (NRP) and tolloid (TLL)-like 2 (NETO2), transcript variant 1
Alternative NameBTCL2; NEOT2
Database LinkNP_060562
Entrez Gene 81831 Human
Entrez Gene 74513 Mouse
Entrez Gene 307757 Rat
FunctionNETO2, neuropilin and tolloid-like protein 2, is a transmembrane protein containing two extracellular CUB domains followed by a low-density lipoprotein receptor class A domain. It also has an intracellular FXNPXY-like motif, which has been shown in other proteins to be essential for the internalization of clathrin coated pits during endocytosis (1). NETO2 is an accessory subunit of neuronal kainate-sensitive glutamate receptors, GRIK2 and GRIK3. It increases kainate-receptor channel activity, slowing the decay kinetics of the receptors, without affecting their expression at the cell surface, and increasing the open probability of the receptor channels (2).
Related PathwayTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - NETO2 antibody [EPR3497]; All lanes : Anti-NETO2 antibody [EPR3497] at 1/1000 dilution.Lane 1 : Human cerebellum lysates.Lane 2 : SH-SY5Y cell lysates.Lane 3 : Human brain lysates.Lysates/proteins at 10 ug per lane.Predicted band size : 60 kDa.
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Western blot - NETO2 antibody [EPR3497]; All lanes : Anti-NETO2 antibody [EPR3497] at 1/1000 dilution.Lane 1 : mouse brain lysates.Lane 2 : rat brain lysates.Lysates/proteins at 10 ug per lane.Predicted band size : 60 kDa.
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