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Home Antibody All anti-NEFM antibodies

Anti-NEFM TRUEMAB Antibody Clone OTI1A4

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA506753 NEFM mouse monoclonal antibody, clone OTI1A4 (formerly 1A4) 100ul $325 In Stock
LC417338 NEFM HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF506753 Carrier-free (BSA/glycerol-free) NEFM mouse monoclonal antibody, clone OTI1A4 (formerly 1A4) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(1)
IF(1)

OriGene Data

ImmunogenFull length human recombinant protein of human NEFM(NP_005373) produced in HEK293T cell.
Clone NameClone OTI1A4 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IF Suggested DilutionsWB 1:1000 -1:4000, IF 1:100
Predicted MW Explanation 102.3 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens neurofilament, medium polypeptide (NEFM), transcript variant 1
Alternative NameNEF3; NF-M; NFM
Database LinkNP_005373
Entrez Gene 4741 Human
FunctionNeurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008].
Related Pathway Amyotrophic lateral sclerosis (ALS)

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NEFM (RC224475, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NEFM.
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Immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY NEFM(RC224475) using Anti-NEFM mouse monoclonal antibody (TA506753) at 1:100 dilution.
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