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Anti-NEFL TRUEMAB Antibody Clone OTI2F5
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for NEFL (NM_006158)
|Human recombinant protein fragment corresponding to amino acids 1-360 of human NEFL (NP_006149) produced in E.coli.|
|| WB 1:2000,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens neurofilament, light polypeptide (NEFL)|
|CMT1F; CMT2E; NF-L; NF68; NFL; PPP1R110|
Entrez Gene 4747 Human
|Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]. |
|ES Cell Differentiation/IPSDruggable Genome Amyotrophic lateral sclerosis (ALS)|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NEFL (RC205920, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NEFL.