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Home Antibody All anti-NEFL antibodies

Anti-NEFL TRUEMAB Antibody Clone OTI2F5

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA801223 NEFL mouse monoclonal antibody, clone OTI2F5 (formerly 2F5) 100ul $379 In Stock
LC416829 NEFL HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF801223 Carrier-free (BSA/glycerol-free) NEFL mouse monoclonal antibody, clone OTI2F5 (formerly 2F5) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(1)

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 1-360 of human NEFL (NP_006149) produced in E.coli.
Clone NameClone OTI2F5 IsotypeIgG2b
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB Suggested Dilutions WB 1:2000,
Predicted MW Explanation 61.3 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens neurofilament, light polypeptide (NEFL)
Alternative NameCMT1F; CMT2E; NF-L; NF68; NFL; PPP1R110
Database LinkNP_006149
Entrez Gene 4747 Human
FunctionNeurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008].
Related PathwayES Cell Differentiation/IPSDruggable Genome Amyotrophic lateral sclerosis (ALS)

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NEFL (RC205920, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NEFL.
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