Home Antibody All anti-NEFL antibodies
Also for NEFL (NM_031783)
|Preparation of bovine spinal cord NF-L|
||Lot dependent; please refer to CoA along with shipment
||WB: 1:10,000, IF: 1:5,000
|total IgY fraction in PBS + 10 mM NaN3.|
|Total IgY fraction
|Rattus norvegicus neurofilament, light polypeptide (Nefl)|
Entrez Gene 83613 Rat
|Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq]. |
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Western blot of rat cortex lysate showing specific immunolableing of the ~ 68k NF-L protein.