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Anti-NEFH Antibody EP673Y


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SKU Description Amount Price Availability*  
  • Rabbit monoclonal antibody against Neurofilament-H(EP673Y)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC412101) , 20ug Explanation
100ul $325 3-7 Days
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human NF-H was used as immunogen.
Clone NameEP673Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1:2,000; IHC: 1:500; ICC: 1:100-250
Predicted MW Explanation 112 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification IgG fraction

Reference Data

Target NameHomo sapiens neurofilament, heavy polypeptide (NEFH)
Alternative NameNFH
Database LinkNP_066554
Entrez Gene 4744 Human
Entrez Gene 380684 Mouse
Entrez Gene 24587 Rat
FunctionNeurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq].
Related PathwayDruggable Genome Amyotrophic lateral sclerosis (ALS)

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Western blot - 200 kD Neurofilament Heavy antibody [EP673Y]; Anti-200 kD Neurofilament Heavy antibody [EP673Y] at 1/2000 dilution + Rat brain lysate.Predicted band size : 112 kDa.Observed band size : 200 kDa .Additional bands at : 75 kDa. We are unsure as to the identity of these extra bands.
Immunohistochemistry (Paraffin-embedded sections) - 200 kD Neurofilament Heavy antibody [EP673Y]; Immunohistochemical analysis of paraffin embedded human brain glyoma using TA303613.
Immunofluorescence - 200 kD Neurofilament Heavy antibody [EP673Y]; Immunofluorescent staining of PC-12 cells using TA303613.


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