Home Antibody All anti-NDUFA5 antibodies
Also for NDUFA5 (NM_005000)
|Recombinant fragment corresponding to a region within amino acids 1 and 116 of NDUFA5 (Uniprot ID#Q16718)|
|Human, Mouse (Predicted: Chimpanzee)
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Chimpanzee (100%)
|Homo sapiens NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 (NDUFA5), transcript variant 1|
|B13; CI-13kB; CI-13KD-B; NUFM; UQOR13|
Entrez Gene 4698 Human
Entrez Gene 68202 Mouse
|The human NDUFA5 gene codes for the B13 subunit of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. The high degree of conservation of NDUFA5 extending to plants and fungi indicates its functional significance in the enzyme complex. The protein localizes to the inner mitochondrial membrane as part of the 7 component-containing, water soluble "iron-sulfur protein" (IP) fraction of complex I, although its specific role is unknown. It is assumed to undergo post-translational removal of the initiator methionine and N-acetylation of the next amino acid. The predicted secondary structure is primarily alpha helix, but the carboxy-terminal half of the protein has high potential to adopt a coiled-coil form. The amino-terminal part contains a putative beta sheet rich in hydrophobic amino acids that may serve as mitochondrial import signal. Related pseudogenes have also been identified on four other chromosomes. [provided by RefSeq]|
| Oxidative phosphorylationMetabolic pathwaysAlzheimer's diseaseParkinson's diseaseHuntington's disease|
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Sample (50 ug of whole cell lysate). A: mouse brain. 15% SDS PAGE. TA308306 diluted at 1:1000.
Sample (30 ug of whole cell lysate). A: Hep G2 . 15% SDS PAGE. TA308306 diluted at 1:1000.
Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using NDUFA5(TA308306) antibody at 1:500 dilution.