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Home Antibody All anti-NDFIP1 antibodies

Anti-NDFIP1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319065
  • Rabbit polyclonal anti-NDFIP1 antibody (NT)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC410830) , 20ug Explanation
100ug 345 3-7 Days
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WB(1)
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Also for NDFIP1 (NM_030571)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenNDFIP1 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human NDFIP1.
Clone Name IsotypeRabbit IgG1
Species ReactivityHuman, Mouse Concentration1 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1-2 ug/ml, ELISA
Buffer100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens Nedd4 family interacting protein 1 (NDFIP1)
Alternative NameN4WBP5
Database LinkNP_085048
Entrez Gene 80762 Human
Entrez Gene 65113 Mouse
FunctionThe NEDD4 family-interacting protein 1 (NDFIP1) belongs to a small group of evolutionarily conserved proteins with three transmembrane domains and is an integral Golgi membrane protein. It is a potential target for ubiquitination by the Nedd4 family of proteins. NDFIP1 is strongly expressed in surviving neurons following acute cortical brain injury, and overexpression in cultured cortical neurons increased survival following growth factor starvation, suggesting that NDFIP1 may play a role in neuronal survival. NDFIP1 and the related protein NDFIP2 are thought to interact with and regulate multiple components of the EGF and PTEN/Akt signaling pathways. Recent studies suggest that NDFIP1 may also play a role in Th17 differentiation by limiting the production of proinflammatory cytokines.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of NDFIP1 in PC-3 cell lysate with NDFIP1 antibody at (A) 0.5 and (B) 1 ug/ml.

 

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