Home Antibody All anti-NCLN antibodies
Anti-NCLN Antibody Polyclonal
Also for NCLN (NM_020170)
|NCLN antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human NCLN.|
|Human, Mouse, Rat
|WB, IHC, IF
||WB: 0.5 ug/ml, IHC: 2.5 ug/ml, IF: 2.5 ug/ml
|NCLN Antibody is supplied in PBS containing 0.02% sodium azide.|
|NCLN Antibody is affinity chromatography purified via peptide column.
|Homo sapiens nicalin (NCLN)|
Entrez Gene 56926 Human
Entrez Gene 103425 Mouse
Entrez Gene 314648 Rat
|NCLN Antibody: Nicalin, along with its binding partner Nomo, is a novel signaling antagonist to Nodals, signaling factors of the TGF-β superfamily that play a key role in vertebrate development. Nicalin is distantly related to Nicastrin, a component of the Alzheimer's disease-associated gamma-secretase, and is thought to have a similar function. Another protein, TMEM147, has also been recently identified as associating with Nicalin and NOMO as part of the gamma-secretase-like complex.|
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Western blot analysis of NCLN in mouse heart tissue lysate with NCLN antibody at 0.5 ug/mL in (A) the absence and (B) the presence of blocking peptide.
Immunohistochemistry of NCLN in human heart tissue with NCLN antibody at 2.5 ug/mL.
Immunofluorescence of NCLN in human heart tissue with NCLN antibody at 20 ug/mL.