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Home Antibody All anti-NANOG antibodies

Anti-NANOG Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306915
  • Rabbit Polyclonal NANOG Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC411030) , 20ug
100ug 325 3-7 Days
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WB(1)
IHC(1)
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Also for NANOG (NM_024865)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenNANOG antibody was raised against a 19 amino acid peptide near the center of human NANOG.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsELISA, WB: 1 - 2 ug/ml, IHC: 5 ug/ml, IF: 20 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens Nanog homeobox (NANOG)
Alternative Namehomeobox transcription factor Nanog; homeobox transcription factor Nanog-delta 48; Nanog homeobox
Database LinkNP_079141
FunctionExpression of NANOG is required for the maintenance of pluripotency in epiblast and embryonic stem (ES) cells as well as for the ability to maintain ES self-renewal independently of LIF/Stat3. The role of NANOG in embryonic development suggested that it might be useful in the creation of stem cells that might be useful in cell replacement therapies in the treatment of several degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing POU5F1 (also known as Oct-4), another germline-specific transcription factor, and the transcription factors Sox2, Klf4 and Lin28 along with c-Myc in mouse fibroblasts. More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing NANOG, Sox2, KlfF4 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine.
Related Pathway
Wnt Signaling Pathway

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WB Image
Western blot analysis of NANOG in human spleen tissue lysate with NANOG antibody at (A) 1 and (B) 2 ug/mL.
IHC Image
Immunohistochemistry of NANOG in human spleen tissue with NANOG antibody at 5 ug/mL.

 

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