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UltraMAB

MUC1 UltraMAB Antibody, Clone UMAB57

UltraMAB™ Antibodies - Validated with 10K Protein Chip

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Specifications Citations Related Products Product Documents
SKU Description Datasheet Price Availability*  
UM800008
  • MUC1 mouse monoclonal antibody,clone UMAB57, 100 ul
$468 In Stock Add to Shopping Cart
UM870008
  • MUC1 mouse monoclonal antibody,clone UMAB57, 30 ul
$120 In Stock Add to Shopping Cart
IHC(5)
10K-CHIP(1)
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Also for MUC1 (NM_001018016)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
Gene NameHomo sapiens mucin 1, cell surface associated (MUC1), transcript variant 2
SynonymsADMCKD; ADMCKD1; CA 15-3; CD227; EMA; H23AG; KL-6; MAM6; MCD; MCKD; MCKD1; MUC-1; MUC-1/SEC;
ImmunogenFull length human recombinant protein of human MUC1 (NP_001018016) produced in HEK293T cell.
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Clone NameClone UMAB57 IsotypeIgG2b
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
Guaranteed Application *IHC, 10K-CHIP Suggested Dilutions IHC 1:100,
BackgroundThis gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011].

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

IHC Image
Immunohistochemical staining of paraffin-embedded Human normal breast tissue and breast adenocarcinoma tissue using anti-MUC1 mouse monoclonal antibody. (UM800008)
IHC Image
Immunohistochemical staining of paraffin-embedded Human normal colon tissue and colorectal cancer tissue using anti-MUC1 mouse monoclonal antibody. (UM800008)
IHC Image
Immunohistochemical staining of paraffin-embedded Human normal lung tissue and lung adenocarcinoma tissue using anti-MUC1 mouse monoclonal antibody. (UM800008)
IHC Image
Immunohistochemical staining of paraffin-embedded Human normal pancreas tissue and pancreatic cancer tissue using anti-MUC1 mouse monoclonal antibody. (UM800008)
IHC Image
Immunohistochemical staining of paraffin-embedded Human normal bladder tissue and bladder cancer tissue using anti-MUC1 mouse monoclonal antibody. (UM800008)
10K-CHIP Image
OriGene overexpression protein microarray chip was immunostained with UltraMAB anti-MUC1 mouse monoclonal antibody (Clone UMAB37). The positive reactive proteins are highlighted with two red arrows in the enlarged subarray. All the positive controls spotted in this subarray are also labeled for clarification. These data show that UltraMAB anti-MUC1 (Clone UMAB57 ) very specifically recognizes MUC1 antigen on OriGene protein microarray chip.

 

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