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Home Antibody All anti-MTHFD1 antibodies

Anti-MTHFD1 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA305850 Goat Anti-MTHFD1 Antibody 100ug $325 3-7 Days
LC416959 MTHFD1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for MTHFD1 (NM_005956)
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OriGene Data

ImmunogenPeptide with sequence RGDLNDCFIPCTPK, from the internal region of the protein sequence according to NP_005947.2.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human, Mouse, Rat Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1-3ug/ml.
Buffer0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase (MTHFD1)
Alternative NameMTHFC; MTHFD
Database LinkNP_005947
Entrez Gene 4522 Human
Entrez Gene 108156 Mouse
Entrez Gene 64300 Rat
FunctionThis gene encodes a protein that possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain. [provided by RefSeq].
Related PathwayStem cell - PluripotencyDruggable Genome Glyoxylate and dicarboxylate metabolismOne carbon pool by folateMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA305850 (1ug/ml) staining of Human Substantia Nigra lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.


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