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Anti-MMP13 TRUEMAB Antibody Clone2F4
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for MMP13 (NM_002427)
|Human recombinant protein fragment corresponding to amino acids 104-471 of human MMP13 (NP_002418) produced in HEK293T cell.|
|| WB 1:4000, IF 1:100,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens matrix metallopeptidase 13 (MMP13)|
|CLG3; MANDP1; MMP-13|
Entrez Gene 4322 Human
|Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]. |
|ProteaseDruggable Genome |
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MMP13 (RC224156, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MMP13.
Anti-MMP13 mouse monoclonal antibody (TA506699) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MMP13(RC224156).