Home Antibody All anti-MFN2 antibodies
Also for MFN2 (NM_014874)
|Synthetic peptide corresponding to residues surrounding amino acid 719 of human Mitofusin 2|
|Human, mouse, rat
||WB: 0.5-4 ug/ml
|100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.|
|Homo sapiens mitofusin 2 (MFN2), transcript variant 1|
|CMT2A; CMT2A2; CPRP1; HSG; MARF|
Entrez Gene 9927 Human
Entrez Gene 170731 Mouse
Entrez Gene 64476 Rat
|Mitofusin 2 (Mfn 2) is mostly expressed in the heart and muscle tissues. It is a transmembrane protein that mediates mitochondria fusion and plays a central role in the maintenance of mitochondrial morphology. A GTPase domain is required for the function of Mitofusin proteins. Mutations in Mfn2 can lead to Charcot-Marie-Tooth disease, a common inherited disorder of the peripheral nervous system. Mfn2 may also be associated with obesity and/or apoptosis.|
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Western blot analysis of Mitofusin 2 in Jurkat cell lysate.