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Home Antibody All anti-ME2 antibodies

Anti-ME2 Antibody EPR7218

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310683
  • Rabbit Monoclonal antibody against ME2
100ul 325 3-7 Days
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WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human ME2 was used as an immunogen.
Clone NameEPR7218 IsotypeTissue culture supernatant
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:50 - 1:100; ICC/IF: 1:100 - 1:250
BufferDoes not react with Mouse. Is unsuitable for Flow Cyt or IP.
Purification pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens malic enzyme 2, NAD(+)-dependent, mitochondrial (ME2), transcript variant 2
Alternative NameODS1
Database LinkNP_001161807
Entrez Gene 4200 Human
FunctionME2 is a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different protein. Certain mutations of ME2 have been shown to increase the risk for idiopathic generalized epilepsy (1).
Related Pathway Pyruvate metabolism

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-ME2 antibody [EPR7218]; All lanes : Anti-ME2 antibody [EPR7218] at 1/1000 dilution.Lane 1 : 293T cell lysate.Lane 2 : Jurkat cell lysate.Lane 3 : HeLa cell lysate.Lane 4 : K562 cell lysate.Lane 5 : MOLT4 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat Anti-rabbit HRP at 1/2000 dilution.Predicted band size : 65 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ME2 antibody [EPR7218]; TA310683, at 1/50 dilution, staining ME2 in Formalin-fixed, Paraffin-embedded Human colon tissue by Immunohistochemistry.
IF Image
Immunocytochemistry/ Immunofluorescence - Anti-ME2 antibody [EPR7218]; TA310683, at 1/100 dilution, staining ME2 in HeLa cells by Immunofluorescence.

 

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