Home Antibody All anti-MAPKAPK5 antibodies
Also for MAPKAPK5 (NM_139078)
|Recombinant fragment contain a sequence corresponding to a region within amino acids 197 and 457 of PRAK (Uniprot ID#Q8IW41)|
|Human (Predicted: Mouse, Chicken, Pig, Rat, Xenopus tropicalis)
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Mouse (96%), Chicken (95%), Pig (97%), Rat (96%), Xenopus tropicalis (90%)
|Homo sapiens mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5), transcript variant 2|
|MAPKAP-K5; MK-5; MK5; PRAK|
Entrez Gene 8550 Human
Entrez Gene 17165 Mouse
Entrez Gene 498183 Rat
|The protein encoded by this gene is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq]|
|Protein KinaseDruggable Genome MAPK signaling pathway|
* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
Sample(30 ug of whole cell lysate). A:293T. B:H1299. 7.5% SDS PAGE. TA308640 diluted at 1:500
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using PRAK(TA308640) antibody at 1:200 dilution.