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Home Antibody All anti-MAP4K4 antibodies

Anti-MAP4K4 Antibody EPR1642(2)

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310673
  • Rabbit Monoclonal antibody against MAP4K4
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC407892) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
FC(1)
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Also for MAP4K4 (NM_001242559)
cDNA Clone shRNA/siRNA Primer Pair Protein Request Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the C-terminus in human MAP4K4 was used as an immunogen.
Clone NameEPR1642(2) IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, FC Suggested DilutionsWB: 1:1000 - 1:10000; FC: 1:1800
BufferpH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4), transcript variant 4
Alternative NameFLH21957; HEL-S-31; HGK; MEKKK4; NIK
Database LinkNP_001229488
Entrez Gene 9448 Human
Entrez Gene 26921 Mouse
Entrez Gene 301363 Rat
FunctionMAP4K4 is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway.
Related PathwayProtein KinaseDruggable Genome MAPK signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-MAP4K4 antibody [EPR1642(2)]; All lanes : Anti-MAP4K4 antibody [EPR1642(2)] at 1/1000 dilution.Lane 1 : 293T cell lysate.Lane 2 : Jurkat cell lysate.Lane 3 : SH-SY5Y cell lysate.Lysates/proteins at 10 ug/ml per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 142 kDa.
FC Image
Flow Cytometry - Anti-MAP4K4 antibody [EPR1642(2)]; Flow Cytometry analysis of permeabilized Jurkat cells labelling MAP4K4 with TA310673 at 1/800 dilution (red). Rabbit IgG (negative control) shown in green.

 

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