Anti-MAP4K4 Antibody, EPR1642(2)

Also for MAP4K4 (NM_001242559)

Gene Name	Homo sapiens mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4), transcript variant 4
Synonyms:	FLH21957; HGK; MEKKK4; NIK
Immunogen	A synthetic peptide corresponding to residues on the C-terminus in human MAP4K4 was used as an immunogen.
Buffer	Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.
Clone Name	EPR1642(2)	Isotype
Species Reactivity	Human, Mouse, Rat	Concentration
Purification	(Protein A or G Sepharose)
Guaranteed Application *	WB, FC	Suggested Dilutions	WB: 1:1,000-10,000;
Background	MAP4K4 is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway.
Related Pathway	MAPK signaling pathway

* Shipping is in business days

* OriGene provides validated application data and protocol, with money back guarantee.

WB Image

Western blot analysis on (A) 293T, (B) Jurkat, and (C) SH-SY5Y cell lysates using anti-MAP4K4 RabMAb.

FC Image

Flow cytometric analysis of permeabilized Jurkat cells using anti-MAP4K4 RabMAb (red) or a rabbit IgG (negative) (green).

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

HRP
Biotin
PE
FITC
DyLight® 488
DyLight® 550
DyLight® 594
DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

OriGene Antibodies in recent publications

Anti-MAP4K4 Antibody EPR1642(2)

TrueMAB™ Antibodies - Made against Authentic Protein Antigens