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Anti-MAP2K7 Antibody EP1455Y
Also for MAP2K7 (NM_145185)
|A synthetic peptide corresponding to residues on the C-terminus of human MKK7 was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
||WB: 1:10000; IP: 1:100; ICC: 1:100 - 1:250; FC: 1:40; IHC-P: Use at an assay dependent dilution
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Homo sapiens mitogen-activated protein kinase kinase 7 (MAP2K7), transcript variant 3|
|JNKK2; MAPKK7; MEK; MEK 7; MKK7; PRKMK7; SAPKK-4; SAPKK4|
|The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined. [provided by RefSeq]. |
EGFR1 Signaling Pathway
MAPK signaling pathway
Toll-like receptor signaling pathway
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Western blot - MEK7 antibody [EP1455Y]; Anti-MEK7 antibody [EP1455Y] at 1/10000 dilution + HeLa cell lysate at 10 ug.Secondary.Goat anti-rabbit HRP antibody at 1/2000 dilution.Predicted band size : 47 kDa.Observed band size : 47 kDa.
Immunohistochemistry (Paraffin-embedded sections) - MEK7 antibody [EP1455Y]; Ab52618 at 1/50 dilution staining human baldder tissue; paraffin embedded.