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Home Antibody All anti-MAP2K7 antibodies

Anti-MAP2K7 Antibody EP1455Y

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SKU Description Amount Price Availability*  
TA303668 Rabbit monoclonal antibody against MKK7 (C-term) (EP1455Y ) 100ul $325 In Stock
LC408043 MAP2K7 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(1)
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Also for MAP2K7 (NM_145185)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the C-terminus of human MKK7 was used as an immunogen.
Clone NameEP1455Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:10000; IP: 1:100; ICC: 1:100 - 1:250; FC: 1:40; IHC-P: Use at an assay dependent dilution
Predicted MW Explanation 47 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant

Reference Data

Target NameHomo sapiens mitogen-activated protein kinase kinase 7 (MAP2K7), transcript variant 3
Alternative NameJNKK2; MAPKK7; MEK; MEK 7; MKK7; PRKMK7; SAPKK-4; SAPKK4
Database LinkNP_660186
Entrez Gene 5609 Human
Entrez Gene 26400 Mouse
Entrez Gene 363855 Rat
FunctionThe protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined. [provided by RefSeq].
Related PathwayProtein KinaseDruggable Genome MAPK signaling pathwayErbB signaling pathwayToll-like receptor signaling pathwayT cell receptor signaling pathwayFc epsilon RI signaling pathwayNeurotrophin signaling pathwayMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - MEK7 antibody [EP1455Y]; Anti-MEK7 antibody [EP1455Y] at 1/10000 dilution + HeLa cell lysate at 10 ug.Secondary.Goat anti-rabbit HRP antibody at 1/2000 dilution.Predicted band size : 47 kDa.Observed band size : 47 kDa.
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Immunohistochemistry (Paraffin-embedded sections) - MEK7 antibody [EP1455Y]; Ab52618 at 1/50 dilution staining human baldder tissue; paraffin embedded.
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