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Home Antibody All anti-MAP2K7 antibodies

Anti-MAP2K7 Antibody EP1455Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303668
  • Rabbit monoclonal antibody against MKK7 (C-term) (EP1455Y )
  • FREE positive control: HEK293T cell transient overexpression lysate (LC408043) , 20ug
100ul 325 In Stock
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WB(1)
IHC(1)
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Also for MAP2K7 (NM_145185)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the C-terminus of human MKK7 was used as an immunogen.
Clone NameEP1455Y IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:10000; IP: 1:100; ICC: 1:100 - 1:250; FC: 1:40; IHC-P: Use at an assay dependent dilution
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant

Reference Data

Target NameHomo sapiens mitogen-activated protein kinase kinase 7 (MAP2K7)
Alternative NameJnkk2; MAPKK7; MKK7; PRKMK7; SAPKK-4; SAPKK4
Database LinkNP_660186
FunctionThe protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined. [provided by RefSeq].
Related Pathway
EGFR1 Signaling Pathway
MAPK signaling pathway
Toll-like receptor signaling pathway

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WB Image
Western blot - MEK7 antibody [EP1455Y]; Anti-MEK7 antibody [EP1455Y] at 1/10000 dilution + HeLa cell lysate at 10 µg.Secondary.Goat anti-rabbit HRP antibody at 1/2000 dilution.Predicted band size : 47 kDa.Observed band size : 47 kDa.
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - MEK7 antibody [EP1455Y]; Ab52618 at 1/50 dilution staining human baldder tissue; paraffin embedded.

 

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