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Home Antibody All anti-M6PRBP1 antibodies

Anti-M6PRBP1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306343
  • Rabbit Polyclonal TIP47 Antibody
100ug 325 3-7 Days
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WB(1)
IHC(1)
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Also for M6PRBP1 (NM_001164189)
cDNA Clone shRNA/siRNA Primer Pair Protein Request Antibody

OriGene Data

ImmunogenTIP47 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human TIP47.
Clone Name IsotypeIgG
Species ReactivityHuman, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 0.5 - 1 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens perilipin 3 (PLIN3), transcript variant 2
Alternative NameM6PRBP1; PP17; TIP47
Database LinkNP_001157661
Entrez Gene 10226 Human
Entrez Gene 316130 Rat
FunctionTail-interacting protein (TIP47) is a cytosolic protein essential for the transport of mannose-6-phosphate receptors (MPRs) from endosomes to the trans-Golgi compartments in cells. TIP47 is recruited from the cytoplasm to the late endosomal surface by the Ras-associated protein Rab9 GTPase, enabling it to bind more efficiently to MPR cytoplasmic domains. Recently, it was shown that TIP47 regulates the expression of Rab9, as expression of siRNA to TIP47 in transfected cells dramatically decreased the half-life of the Rab9 protein in addition to stabilizing the subcellular localization of Rab9. At least two isoforms of TIP47 are known to exist.
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of TIP47 in Daudi cell lysate with TIP47 antibody at (A) 0.5 and (B) 1 ug/ml.
IHC Image
Immunohistochemistry of TIP47 in rat liver tissue with TIP47 antibody at 10 ug/ml.

 

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