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Home Antibody All anti-LZTS2 antibodies

Anti-LZTS2 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA320050
  • Rabbit Polyclonal LZTS2 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC410123) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for LZTS2 (NM_032429)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenLZTS2 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human LZTS2.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 ug/ml, IHC: 2.5 ug/ml, IF: 20 ug/ml
BufferLZTS2 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification LZTS2 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens leucine zipper, putative tumor suppressor 2 (LZTS2)
Alternative NameLAPSER1
Database LinkNP_115805
Entrez Gene 84445 Human
Entrez Gene 226154 Mouse
FunctionLZTS2 Antibody: The leucine zipper putative tumor suppressor 2 (LZTS2, also known as LAPSER1), a member of the LZTS family, is a negative regulator of the Wnt signaling pathway. It represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. LZTS2 is involved in cytokinesis and regulates katanin-mediated microtubule severing and release from the centrosome. LZTS2 may negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. LZTS2 is highly expressed in testis and prostate, but it is deleted in multiple cancers, including prostate tumors, suggesting that LZTS2 acts as a potential tumor suppressor.
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of LZTS2 in human kidney tissue lysate with LZTS2 antibody at 1 ug/mL.
IHC Image
Immunohistochemistry of LZTS2 in human kidney tissue with LZTS2 antibody at 2.5 ug/mL.
IF Image
Immunofluorescence of LZTS2 in human kidney tissue with LZTS2 antibody at 20 ug/mL.

 

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