Home Antibody All anti-LZTS2 antibodies
Anti-LZTS2 Antibody Polyclonal
Also for LZTS2 (NM_032429)
|LZTS2 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human LZTS2.|
|WB, IHC, IF
||WB: 1 ug/ml, IHC: 2.5 ug/ml, IF: 20 ug/ml
|LZTS2 Antibody is supplied in PBS containing 0.02% sodium azide.|
|LZTS2 Antibody is affinity chromatography purified via peptide column.
|Homo sapiens leucine zipper, putative tumor suppressor 2 (LZTS2)|
Entrez Gene 84445 Human
Entrez Gene 226154 Mouse
|LZTS2 Antibody: The leucine zipper putative tumor suppressor 2 (LZTS2, also known as LAPSER1), a member of the LZTS family, is a negative regulator of the Wnt signaling pathway. It represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. LZTS2 is involved in cytokinesis and regulates katanin-mediated microtubule severing and release from the centrosome. LZTS2 may negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. LZTS2 is highly expressed in testis and prostate, but it is deleted in multiple cancers, including prostate tumors, suggesting that LZTS2 acts as a potential tumor suppressor. |
|Druggable Genome |
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Western blot analysis of LZTS2 in human kidney tissue lysate with LZTS2 antibody at 1 ug/mL.
Immunohistochemistry of LZTS2 in human kidney tissue with LZTS2 antibody at 2.5 ug/mL.
Immunofluorescence of LZTS2 in human kidney tissue with LZTS2 antibody at 20 ug/mL.