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Home Antibody All anti-LZTR1 antibodies

Anti-LZTR1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306929
  • Rabbit Polyclonal LZTR1 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC416434) , 20ug
100ug 325 3-7 Days
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WB(1)
IHC(1)

OriGene Data

ImmunogenLZTR1 antibody was raised against a 14 amino acid peptide near the amino terminus of human LZTR1.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsELISA, WB: 1 - 2 ug/ml, IHC: 5 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens leucine-zipper-like transcription regulator 1 (LZTR1)
Alternative NameBTBD29; LZTR-1; SWNTS2
Database LinkNP_006758
FunctionLZTR1, a member of the BTB-kelch superfamily, was initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Golgi complex. Deletion of this gene may be associated with DiGeorge syndrome, a developmental field defect involving the third and fourth pharyngeal pouches, causing the absence of thymus and parathyroid glands, congenital cardiac abnormalities and facial dysmorphism. LZTR1 is tyrosine phosphorylated and subsequently degraded upon induction of apoptosis.
Related Pathway

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WB Image
Western blot analysis of LZTR1 in human heart tissue lysate with LZTR1 antibody at (A) 1 and (B) 2 ug/mL.
IHC Image
Immunohistochemistry of LZTR1 in mouse heart tissue with LZTR1 antibody at 5 ug/mL.

 

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