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Home Antibody All anti-LY86 antibodies

Anti-LY86 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA306330 Rabbit Polyclonal MD-1 Antibody 100ug $325 3-7 Days
LC401367 LY86 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenMD-1 antibody was raised against a 15 amino acid peptide from near the center of human MD-1.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1 - 2 ug/mL, ICC: 2.5 ug/mL
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens lymphocyte antigen 86 (LY86)
Alternative NamedJ80N2.1; MD-1; MD1; MMD-1
Database LinkNP_004262
Entrez Gene 9450 Human
Entrez Gene 17084 Mouse
Entrez Gene 291359 Rat
FunctionToll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins such as RP105, a recently identified homolog of TLR4. This protein, in association with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway. While MD-2 can directly bind to LPS, one of the activating molecules of TLR4, the function of MD-1 is less well-known. It has been suggested however, that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes.
Related PathwaySecreted Protein

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of MD-1 in Daudi cell lysate with MD-1 antibody at (A) 1 and (B) 2 ug/ml.

IHC Image
Immunohistochemistry of MD-1 in human spleen tissue with MD-1 antibody at 2.5 ug/ml.


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