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Home Antibody All anti-LRRFIP2 antibodies

Anti-LRRFIP2 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319772
  • Rabbit Polyclonal LRRFIP2 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC427402) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for LRRFIP2 (NM_001134369)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenLRRFIP2 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human LRRFIP2.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 0.5 and 1 ug/ml, IHC: 5 ug/ml, IF: 20 ug/ml
BufferLRRFIP2 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification LRRFIP2 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens leucine rich repeat (in FLII) interacting protein 2 (LRRFIP2), transcript variant 3
Alternative NameHUFI-2
Database LinkNP_001127841
Entrez Gene 9209 Human
Entrez Gene 71268 Mouse
Entrez Gene 301035 Rat
FunctionLRRFIP2 Antibody: The leucine-rich repeat FLI-I-interacting protein 2 (LRRFIP2), like the related protein LRRFIP1, was identified in a yeast two-hybrid system through binding to the LRR domain of human FLI. It can activate the Wnt signaling pathway in cultured cells and is thought to be a component of the Wnt signaling pathway that modulates Wnt signaling through interactions with Disheveled to increase the cellular levels and transcription activity of beta-catenin. LRRFIP2 has recently been characterized as a positive regulator of the TLR4 signaling pathway for activating NF-κB during the early host response to LPS stimulation through binding to the TLR adaptor protein MyD88, and that this interaction with MyD88 is governed by phosphorylation of specific residues in LRRFIP2.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of LRRFIP2 in rat colon tissue lysate with LRRFIP2 antibody at (A) 0.5 and (B) 1 ug/mL.
IHC Image
Immunohistochemistry of LRRFIP2 in human colon tissue with LRRFIP2 antibody at 5 ug/mL.
IF Image
Immunofluorescence of LRRFIP2 in human colon tissue with LRRFIP2 antibody at 20 ug/mL.

 

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