OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
Home Antibody All anti-LRP6 antibodies

Anti-LRP6 Antibody EPR2423(2)


Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
  • Rabbit monoclonal antibody against LRP6(clone EPR2423(2))
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419396) , 20ug Explanation
100ul $325 3 Weeks

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart


OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human LRP6 was used as an immunogen.
Clone NameEPR2423(2) IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IF Suggested DilutionsWB: 1:1000 - 1:10000; ICC/IF: 1:100 - 1:250
Predicted MW Explanation 180 kDa
BufferpH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,IHC-P or IP.

Reference Data

Target NameHomo sapiens low density lipoprotein receptor-related protein 6 (LRP6)
Alternative NameADCAD2
Database LinkNP_002327
Entrez Gene 4040 Human
Entrez Gene 16974 Mouse
Entrez Gene 312781 Rat
FunctionLRP6 (low-density lipoprotein receptor-related protein 6) is a single span transmembrane Wnt receptor that interacts with Axin to promote the Wnt-dependent accumulation of beta-catenin. Cells treated with Wnt quickly induce plasma membrane-associated LRP6 aggregates. The aggregates are phosphorylated, and then promote Axin recruitment and beta-catenin stabilization. LRP6 is internalized with caveolin and components of this endocytic pathway are required not only for Wnt-3a-induced internalization of LRP6 but also for accumulation of beta-catenin (1-2).
Related PathwayTransmembraneDruggable Genome Wnt signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-LRP6 antibody [EPR2423(2)]; All lanes : Anti-LRP6 antibody [EPR2423(2)] at 1/1000 dilution.Lane 1 : HeLa cell lysates .Lane 2 : HepG2 cell lysates .Lane 3 : 293T cell lysates .Lane 4 : Jurkat cell lysates .Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 180 kDa.
Immunocytochemistry/ Immunofluorescence - Anti-LRP6 antibody [EPR2423(2)]; Immunofluorescence analysis of HeLa cells labelled with TA307797 at 1/100 dilution.


Inc 5000 Healthcare Company
All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title