Invalid object name 'antibody_LocusMapping'. Anti-LOX Antibody, Clone 10D11 - OriGene
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Anti-LOX TRUEMAB Antibody Clone 10D11

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA500870
  • LOX mouse monoclonal antibody, clone 10D11
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400843) , 20ug Explanation
100ul 325 In Stock
CF500870
  • Carrier-free (BSA/glycerol-free) LOX mouse monoclonal antibody, clone 10D11
100ug $450 3-4 weeks
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WB(1)
IHC(7)
IF(1)
FC(2)
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Also for LOX (NM_002317)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 22-168 of human LOX (NP_002308) produced in HEK293T cell.
Clone NameClone 10D11 IsotypeIgG1
Species ReactivityHuman Concentration0.68 mg/ml
Guaranteed Application *WB, IHC, IF, FC Suggested DilutionsWB 1:1000, IHC 1:150, IF 1:100, FLOW 1:100,
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens lysyl oxidase (LOX), transcript variant 1
Alternative NameMGC105112
Database LinkNP_002308
FunctionThe protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LOX (RC213323, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-LOX.
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-LOX mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA500870)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-LOX mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA500870)
IHC Image
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-LOX mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA500870)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-LOX mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA500870)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-LOX mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA500870)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-LOX mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA500870)
IHC Image
Immunohistochemical staining of paraffin-embedded Human lymph node tissue using anti-LOX mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA500870)
IF Image
Anti-LOX mouse monoclonal antibody (TA500870) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY LOX(RC213323).
FC Image
Flow cytometric Analysis of Hela cells, using anti-LOX antibody(TA500870),(Red), compared to a nonspecific negative control antibody,(Blue).
FC Image
Flow cytometric Analysis of Jurkat cells, using anti-LOX antibody(TA500870),(Red), compared to a nonspecific negative control antibody,(Blue).

 

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