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Anti-LMAN1 TRUEMAB Antibody Clone OTI1B8
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for LMAN1 (NM_005570)
|Full length human recombinant protein of human LMAN1 (NP_005561) produced in HEK293T cell.|
|Human, Dog, Rat, Monkey
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens lectin, mannose-binding, 1 (LMAN1)|
|ERGIC-53; ERGIC53; F5F8D; FMFD1; gp58; MCFD1; MR60|
Entrez Gene 3998 Human
Entrez Gene 116666 Rat
Entrez Gene 697449 Monkey
Entrez Gene 476186 Dog
|The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished. [provided by RefSeq]. |
|TransmembraneDruggable Genome |
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LMAN1 (RC207088, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-LMAN1.
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-LMAN1 monoclonal antibody.