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Home All anti-LMAN1 antibodies

Anti-LMAN1 Antibody EPR6979

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA310660
  • Rabbit Monoclonal antibody against LMAN1
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401709) , 20ug
100ul $325 3-7 Days
TA802519S
  • Purified GAPDH mouse monoclonal antibody (Loading control), clone 2D9
30ul
$100
$50*
In Stock
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* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
WB(1)
IHC(2)
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Also for LMAN1 (NM_005570)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human LMAN1 was used as an immunogen.
Clone NameEPR6979 Isotype
Species ReactivityHuman, Mouse, Rat Concentration
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1,000 - 10,000; ICC: 1:100 - 250; IP: 1:10 - 100;
BufferStore at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.

Reference Data

Target NameHomo sapiens lectin, mannose-binding, 1 (LMAN1)
Alternative NameERGIC-53; ERGIC53; F5F8D; FMFD1; gp58; MCFD1; MR60
Database LinkNP_005561
FunctionLMAN1 is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. It is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in LMAN1 are associated with a coagulation defect. Using positional cloning, it was identified to lead to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished (1).
Related Pathway

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WB Image
Western blot analysis on (A) HeLa, (B) 293T, (C) SH-SY5Y, (D) NCI-H460, (E) Jurkat, and (F) JAR cell lysates using anti-LMAN1 RabMAb.
IHC Image
Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-LMAN1 RabMAb.
IHC Image
Immunohistochemical analysis of paraffin-embedded human papillary carcinoma of thyroid gland tissue using anti-LMAN1 RabMAb.

 

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