Homo sapiens LIM domain kinase 1 (LIMK1), transcript variant 1
Synonyms:
LIMK; LIMK-1
Immunogen
A synthetic peptide corresponding to residues near the N-terminus of human LIMK1 was used as an immunogen.
Buffer
Store at -20C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
LIMK1 belongs to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is likely to be a component of an intracellular signaling pathway and may be involved in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome (1).
Related Pathway
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