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Home Antibody All anti-LGI1 antibodies

Anti-LGI1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306536
  • Rabbit Polyclonal LGI1 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401572) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IHC(1)

OriGene Data

ImmunogenLGI1 antibody was raised against a 14 amino acid peptide from near the center of human LGI1.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens leucine-rich, glioma inactivated 1 (LGI1)
Alternative NameADLTE; ADPAEF; ADPEAF; EPITEMPIN; EPT; ETL1; IB1099
Database LinkNP_005088
Entrez Gene 9211 Human
Entrez Gene 56839 Mouse
Entrez Gene 252892 Rat
FunctionThe leucine-rich, glioma inactivated gene 1 (LGI1) was first identified as a candidate tumor suppressor gene for glioma and may play a role in other cancers. LGI1 is a member of a family of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 serves as a ligand to ADAM22, a metalloprotease localized at the synapse. Mutations in LGI1 account for nearly half of autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Two isoforms of LGI1 are known to exist; this LGI1 antibody will recognize only the longer form. This LGI1 antibody is predicted to be specific to LGI1 and not recognize other LGI proteins.
Related PathwaySecreted ProteinDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of LGI1 in HeLa cell lysate with LGI1 antibody at 2 ug/ml.
IHC Image
Immunohistochemical staining of human brain tissue using LGI1 antibody at 2.5 ug/ml.

 

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