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Anti-LEFTY2 Antibody EPR5444
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Also for LEFTY2 (NM_001172425)
|A synthetic peptide corresponding to residues on the C-terminus in human Lefty was used as an immunogen. This antibody recognizes Lefty1 and Lefty2.|
|Human, Mouse, Rat
||WB: 1:1,000 - 10,000; IHC 1:250 - 500; FC: 1:10 - 100;
|Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.|
|Homo sapiens left-right determination factor 2 (LEFTY2), transcript variant 2|
|EBAF; LEFTA; LEFTYA; TGFB4|
|Lefty is a member of the TGF-beta family of proteins. It is secreted and plays a role in left-right asymmetry determination of organ systems during development. Lefty may also play a role in endometrial bleeding. Mutations in Lefty have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of Lefty in the endometrium (1). |
TGF Beta Signaling Pathway
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Western blot analysis on (A) HeLa, (B) 293T, and (C) Caco-2 cell lysates using anti-Lefty RabMAb.