Home Antibody All anti-LBP antibodies
|Recombinant fragment corresponding to a region within amino acids 166 and 467 of LBP (Uniprot ID#P18428)|
||Lot dependent; please refer to CoA along with shipment
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens lipopolysaccharide binding protein (LBP)|
Entrez Gene 3929 Human
|The protein encoded by this gene is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). Finally, this gene is found on chromosome 20, immediately downstream of the BPI gene. [provided by RefSeq]|
|Secreted ProteinDruggable Genome Toll-like receptor signaling pathway|
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Sample(30 ug whole cell lysate). A:H1299. 7.5% SDS PAGE. TA308490 diluted at 1:500
Immunohistochemical analysis of paraffin-embedded Gastric N+T, using LBP(TA308490) antibody at 1:100 dilution.