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Home Antibody All anti-LASS1 antibodies

Anti-LASS1 Antibody EPR5816(2)

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA310653
  • Rabbit Monoclonal antibody against LASS1
100ul $325 3-7 Days
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WB(1)
Assay(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human LASS1 was used as an immunogen.
Clone NameEPR5816(2) IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY Suggested DilutionsWB: 1:1000 - 1:10000
BufferpH: 7.20; Preservative: 0.01% Sodium azide; Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Note Is unsuitable for ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens ceramide synthase 1 (CERS1), transcript variant 1
Alternative NameEPM8; LAG1; LASS1; UOG1
Database LinkNP_067090
Entrez Gene 10715 Human
FunctionLASS1 is part of a group of proteins is characterized by a polybasic proteolytic processing site that is cleaved to produce a mature protein containing seven conserved cysteine residues. Studies in yeast suggest that LASS1 is involved in aging (1). LASS1 may be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells, it is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked stearoyl- (C18) ceramide) in a fumonisin B1-independent manner (2).
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-LASS1 antibody [EPR5816(2)]; Anti-Ceramide synthase 1 antibody [EPR5816(2)] at 1/1000 dilution + Human fetal brain lysate at 10 ug.Secondary.Goat Anti-rabbit HRP at 1/2000 dilution
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Other-Anti-Ceramide synthase 1 antibody [EPR5816(2)](TA310653); Equilibrium disassociation constant (KD)..
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