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Home Antibody All anti-Klra2 antibodies

Anti-Klra2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306724
  • Rabbit Polyclonal KLRA2 Antibody
100ug 325 3-7 Days
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WB(1)
IHC(1)

OriGene Data

ImmunogenKLRA2 antibody was raised against a 14 amino acid peptide near the carboxy terminus of mouse KLRA2.
Clone Name IsotypeIgG
Species ReactivityMouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsELISA, WB: 0.5 - 1 ug/ml, IHC: 2.5 ug/ml, IF: 20 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameMus musculus killer cell lectin-like receptor, subfamily A, member 2 (Klra2), transcript variant 2
Alternative NameKlra30; Ly49b
Database LinkNP_032488
FunctionKLRA2 (also known as Ly49B) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA2 is thought to be an inhibitory receptor and associates with the protein tyrosine phosphatases SHP1, SHP2, and SHIP in transfected cells. This antibody is predicted to not cross-react with other LY49 receptors.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of KLRA2 in mouse spleen tissue lysate with KLRA2 antibody at (A) 0.5 and (B) 1 ug/mL.
IHC Image
Immunohistochemistry of KLRA2 in mouse spleen tissue with KLRA2 antibody at 2.5 ug/mL.

 

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