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Home Antibody All anti-KRT7 antibodies

Anti-KRT7 Antibody EP1620Y

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SKU Description Amount Price Availability*  
TA301054
  • Rabbit Monoclonal Antibody against KRT7 (Clone EP1620Y)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401707) , 20ug Explanation
100ul $325 3-7 Days
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WB(1)
IF(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the C-terminus of human CK-7 was used as an immunogen.
Clone NameEP1620Y IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IF Suggested DilutionsWB: 1: 10,000~20,000; ICC: 1:250; FC: 1:20; IP: 1:50
Predicted MW Explanation 51 kDa
BufferpH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens keratin 7, type II (KRT7)
Alternative NameCK7; K2C7; K7; SCL
Database LinkNP_005547
Entrez Gene 3855 Human
FunctionCytokeratins are cytoplasmic intermediate filament proteins expressed by epithelial cells. Keratin 7 (CK7) is expressed in a wide range of epithelial structures in humans. The expression pattern in mice is similar to the reported human distribution, with substantial expression observed in lung, bladder, mesothelium, hair follicle, and ductal structures (1). Protein expression levels of CK7 appear significantly higher in chromophobe RCC compared to oncocytoma (p < 0.001). Studies provide further evidence that CK7 and parvalbumin immunostains may be useful in differentiating oncocytoma from chromophobe RCC in problematic cases (2). Also, the pattern of immunohistochemical expression of CK 7 along with CK 20 is commonly used to assess possible primary sites of metastatic carcinomas (3).
Related PathwayES Cell Differentiation/IPS

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Cytokeratin 7 antibody [EP1620Y]; Anti-Cytokeratin 7 antibody [EP1620Y] at 1/20000 dilution + HeLa cell lysate at 10 ug.Secondary.HRP conjugated Goat anti-Rabbit at 1/2000 dilution.Predicted band size : 51 kDa.Observed band size : 51 kDa.
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Immunocytochemistry/ Immunofluorescence - Cytokeratin 7 antibody [EP1620Y]; HeLa cells stained using TA301054 at 1/250 dilution.
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