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Anti-KRT7 Antibody EP1620Y
Also for KRT7 (NM_005556)
|A synthetic peptide corresponding to residues near the C-terminus of human CK-7 was used as an immunogen.|
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1: 10,000~20,000; ICC: 1:250; FC: 1:20; IP: 1:50
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
|Tissue culture supernatant
|Does not react with Mouse, Rat
|Homo sapiens keratin 7 (KRT7)|
|CK7; K2C7; K7; SCL|
|Cytokeratins are cytoplasmic intermediate filament proteins expressed by epithelial cells. Keratin 7 (CK7) is expressed in a wide range of epithelial structures in humans. The expression pattern in mice is similar to the reported human distribution, with substantial expression observed in lung, bladder, mesothelium, hair follicle, and ductal structures (1). Protein expression levels of CK7 appear significantly higher in chromophobe RCC compared to oncocytoma (p < 0.001). Studies provide further evidence that CK7 and parvalbumin immunostains may be useful in differentiating oncocytoma from chromophobe RCC in problematic cases (2). Also, the pattern of immunohistochemical expression of CK 7 along with CK 20 is commonly used to assess possible primary sites of metastatic carcinomas (3). |
EGFR1 Signaling Pathway
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Western blot - Cytokeratin 7 antibody [EP1620Y]; Anti-Cytokeratin 7 antibody [EP1620Y] at 1/20000 dilution + HeLa cell lysate at 10 µg.Secondary.HRP conjugated Goat anti-Rabbit at 1/2000 dilution.Predicted band size : 51 kDa.Observed band size : 51 kDa.
Immunocytochemistry/ Immunofluorescence - Cytokeratin 7 antibody [EP1620Y]; HeLa cells stained using TA301054 at 1/250 dilution.