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Home Antibody All anti-KRT18 antibodies

Anti-KRT18 Antibody EPR1626

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307738
  • Rabbit monoclonal antibody against Cytokeratin 18(clone EPR1626)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400083) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(8)
IF(1)
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Also for KRT18 (NM_000224)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the C-terminus of human Cytokeratin 18 was used as an immunogen.
Clone NameEPR1626 IsotypeTissue culture supernatant
Species ReactivityRat, Human (Does not react with: Mouse) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsIHC-Fr: Use at an assay dependent dilution; WB: 1:10000 - 1:50000; IHC-P: 1:250 - 1:500; ICC/IF: 1:250 - 1:500
BufferDoes not react with Mouse. Is unsuitable for Flow Cyt or IP.
Purification pH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens keratin 18 (KRT18), transcript variant 1
Alternative NameCYK18; K18
Database LinkNP_000215
Entrez Gene 3875 Human
Entrez Gene 294853 Rat
FunctionKeratin polypeptides 8 and 18 (K8/18) are intermediate filament phosphoglycoproteins that are expressed preferentially in glandular epithelia. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells (1-3). Together with actin microfilaments and microtubules, keratin filaments make up the cytoskeletons of vertebrate epithelial cells, forming alpha-helical coiled-coil dimers which associate laterally and end-to-end to form 10-nm diameter filaments (4).
Related Pathway
EGFR1 Signaling Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-Cytokeratin 18 antibody [EPR1626]; All lanes : Anti-Cytokeratin 18 antibody [EPR1626] at 1/10000 dilution.Lane 1 : MCF7 cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : Jurkat cell lysate.Lane 4 : A431 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-rabbit HRP conjugated antibody at 1/2000 dilution.Predicted band size : 48 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cytokeratin 18 antibody [EPR1626]; Immunohistochemical analysis of paraffin embedded Human gastric adenocarcinoma tissue labelling Cytokeratin 18 with TA307738 at 1/250.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cytokeratin 18 antibody [EPR1626]; Immunohistochemical analysis of paraffin embedded Human breast tissue labelling Cytokeratin 18 with TA307738 at 1/250.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Cytokeratin 18 antibody [EPR1626](TA307738); TA307738 showing negative staining in Normal brain tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Cytokeratin 18 antibody [EPR1626](TA307738); TA307738 showing positive staining in Prostatic carcinoma tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Cytokeratin 18 antibody [EPR1626](TA307738); TA307738 showing negative staining in Skeletal muscle tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Cytokeratin 18 antibody [EPR1626](TA307738); TA307738 showing positive staining in Breast carcinoma tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Cytokeratin 18 antibody [EPR1626](TA307738); TA307738 showing positive staining in Lung adenocarcinoma tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Cytokeratin 18 antibody [EPR1626](TA307738); TA307738 showing negative staining in Cervical squamous carcinoma tissue.
IF Image
Immunocytochemistry/ Immunofluorescence - Anti-Cytokeratin 18 antibody [EPR1626]; Immunofluorescence analysis of HeLa cells labelling Cytokeratin 18 with TA307738 at 1/250.

 

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