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Home Antibody All anti-KRT14 antibodies

Anti-KRT14 Antibody EPR1612

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307694
  • Rabbit monoclonal antibody against Cytokeratin 14(clone EPR1612)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424667) , 20ug
100ul 325 3-7 Days
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WB(2)
IHC(8)
Assay(1)
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Also for KRT14 (NM_000526)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Cytokeratin 14 was used as an immunogen.
Clone NameEPR1612 IsotypeTissue culture supernatant
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, IHC Suggested DilutionsWB: 1:10000 - 1:50000; IHC-P: 1:250 - 1:500; ICC: 1:250 - 1:500
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens keratin 14 (KRT14)
Alternative NameCK14; EBS3; EBS4; K14; NFJ
Database LinkNP_000517
FunctionKeratins are cytoplasmic intermediate filament proteins expressed by epithelial cells. Cytokeratin 14 (CK-14) is a 50-kDa keratin expressed in abundance in human epidermal cells (1). During anagen, cell proliferation in the germinative matrix of the hair follicle gives rise to the fiber and inner root sheath. The transition from anagen to telogen is marked by downregulation of hair cortical specific keratins and the appearance of CK-14 in the epithelial sac to which the telogen hair fiber is anchored (2). A family with recessive epidermolysis bullosa simplex lacked expression of the basal cell keratin 14. The patients had severe generalized skin blistering that improved slightly with age. The basal cells of the patients did not express keratin 14 and contained no keratin intermediate filaments. The expression of keratin 5, the obligate copolymer of keratin 14, was slightly reduced (3).
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Cytokeratin 14 antibody [EPR1612]; Anti-Cytokeratin 14 antibody [EPR1612] at 1/10000 dilution + Human skin lysate at 10 µg.Predicted band size : 52 kDa.
WB Image
Western blot - Cytokeratin 14 antibody [EPR1612]; Anti-Cytokeratin 14 antibody [EPR1612] at 1/10000 dilution + A431 cell lysate at 10 µg.Predicted band size : 52 kDa.
Assay Image
Other-Anti-Cytokeratin 14 antibody [EPR1612](TA307694); Equilibrium disassociation constant (KD)..
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Cytokeratin 14 antibody [EPR1612]; TA307694, at a 1/250 dilution, staining Cytokeratin 14 in paraffin embedded Human skin tissue by Immunohistochemistry.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Cytokeratin 14 antibody [EPR1612]; TA307694, at a 1/250 dilution, staining Cytokeratin 14 in paraffin embedded Human squamous cell cervical carcinoma tissue by Immunohistochemistry.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Cytokeratin 14 antibody [EPR1612]; TA307694, at a 1/250 dilution, staining Cytokeratin 14 in paraffin embedded Human tonsil tissue by Immunohistochemistry.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Cytokeratin 14 antibody [EPR1612](TA307694); TA307694 showing positive staining in Normal prostate basal epithelium tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Cytokeratin 14 antibody [EPR1612](TA307694); TA307694 showing negative staining in Normal kidney tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Cytokeratin 14 antibody [EPR1612](TA307694); TA307694 showing negative staining in Breast carcinoma tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Cytokeratin 14 antibody [EPR1612](TA307694); TA307694 showing negative staining in Colonic adenocarcinoma tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Cytokeratin 14 antibody [EPR1612](TA307694); TA307694 showing positive staining in Normal skin tissue.

 

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