Homo sapiens karyopherin alpha 4 (importin alpha 3) (KPNA4)
IPOA3; QIP1; SRP3
Peptide with sequence C-NSSANVPTEGFQF, from the C Terminus of the protein sequence according to NP_002259.1.
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Human. Mouse, Rat, Dog
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. (Protein A or G Sepharose)
Guaranteed Application *
ELISA: 1/32,000. WB: 0.2-1µg/ml. IHC: 3µg/ml.
The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.
* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.