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Anti-KLK2 Antibody EPR6676
Also for KLK2 (NM_001002231)
|A synthetic peptide corresponding to residues in human KLK2 was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000; ICC/IF: 1:50 - 1:100
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt,IHC-P or IP.
|Homo sapiens kallikrein-related peptidase 2 (KLK2), transcript variant 2|
|hGK-1; hK2; KLK2A2|
|KLK2 is a serine protease produced by secretory epithelial cells in the prostate (1). It is a glandular kallikrein that cleaves Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin (2). KLK2 can activate the proforms of PSA (prostate-specific antigen) and urokinase type plasminogen activator and inactivate plasminogen activator inhibitor-1, suggesting a possible role in a proteolytic cascade associated with prostate cancer. Thus, it may promote tumor growth, and metastasis and inhibition of KLK2 activity may, therefore, slow down tumor spread (1).|
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Western blot - Anti-Kallikrein 2 antibody [EPR6676]; All lanes : Anti-Kallikrein 2 antibody [EPR6676] at 1/1000 dilution.Lane 1 : LnCaP lysate.Lane 2 : MOLT4 lysate.Lane 3 : Human seminoma lysate.Lane 4 : PC3 lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 29 kDa.
Other-Anti-Kallikrein 2 antibody [EPR6676](ab124899); Equilibrium disassociation constant (KD)..