OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-KL antibodies

Anti-KL Antibody Polyclonal

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319778
  • Rabbit Polyclonal KLOTHO Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC417748) , 20ug
100ug 325 In Stock
Add to Shopping Cart
WB(1)
IHC(1)
IF(1)
spacer
Also for KL (NM_004795)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenKLOTHO antibody was raised against a 16 amino acid synthetic peptide near the center of human KLOTHO.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 - 2 ug/ml, IHC: 2.5 ug/ml, IF: 20 ug/ml
BufferKLOTHO Antibody is supplied in PBS containing 0.02% sodium azide.
Purification KLOTHO Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens klotho (KL)
Alternative NameOTTHUMP00000018796; klotho
Database LinkNP_004786
FunctionKLOTHO Antibody: KLOTHO is the systemic anti-aging hormone within the glycosidase1 superfamily. It encodes a type I membrane protein that is abundant in the kidney and brain. In mice, a deficiency in KLOTHO expression leads to various systemic phenotypes resembling human aging such as arteriosclerosis, osteoporosis, and skin atrophy together with growth retardation, short life-span and infertility. Transgenic mice overexpressing KLOTHO have an extended life span by inhibiting insulin/IGF1 signaling. KLOTHO is involved in the regulation of calcium/phosphorus homeostasis by inhibiting the synthesis of active vitamin D and identified as a potential tumor suppressor.
Related Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of KLOTHO in rat heart tissue lysate with KLOTHO antibody at (A) 1 and (B) 2 ug/mL.
IHC Image
Immunohistochemistry of KLOTHO in mouse heart tissue with KLOTHO antibody at 2.5 ug/mL.
IF Image
Immunofluorescence of KLOTHO in mouse heart tissue with KLOTHO antibody at 20 ug/mL.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title