OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-KIAA1524 antibodies

Anti-KIAA1524 Antibody 2G10

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA301640
  • Mouse Monoclonal Antibody against CIP2A (2G10)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC412250) , 20ug
100ul 325 In Stock
Add to Shopping Cart
WB(1)
spacer
Also for KIAA1524 (NM_020890)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA C-terminal portion of the human p90 protein.
Clone Name2G10 IsotypeIgG2b kappa
Species Reactivityhuman Concentration1.8mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.5 ug/ml, IF: 1: 100
BufferTris-glycine, 150mM NaCl and 0.05% sodium azide
Purification protein G purified

Reference Data

Target NameHomo sapiens KIAA1524 (KIAA1524)
Alternative NameCIP2A; p90
Database LinkNP_065941
FunctionInhibition of protein phosphatase 2A (PP2A) activity has been identified as a prerequisite for the transformation of human cells. The protein, designated Cancerous Inhibitor of PP2A (CIP2A), interacts directly with the oncogenic transcription factor c-Myc, inhibits PP2A activity toward c-Myc serine 62 (S62), and thereby prevents c-Myc proteolytic degradation. In addition to its function in c-Myc stabilization, CIP2A promotes anchorage-independent cell growth and in vivo tumor formation. The oncogenic activity of CIP2A is demonstrated by transformation of human cells by overexpression of CIP2A. Importantly, CIP2A is overexpressed in two common human malignancies, head and neck squamous cell carcinoma (HNSCC) and colon cancer.
Related Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Detection of CIP2A in HeLa whole cell lysate

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title