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Home Antibody All anti-KCNMB4 antibodies

Anti-KCNMB4 Antibody S18A-3

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA326489
  • Mouse Monoclonal Anti-BKBeta4 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC415209) , 20ug
100µg 325 3-7 Days
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IHC(1)
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Also for KCNMB4 (NM_014505)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenFusion protein amino acids 45-167 (entire extracellular domain) of mouse BKBeta4,
Clone NameS18A-3 IsotypeIgG2a
Species ReactivityHuman, Mouse, Rat. Concentration1mg/mL
Guaranteed Application *IHC Suggested DilutionsWB: 1ug/ml, IHC: 0.1-1ug/ml, IF: 1-10ug/ml
BufferPBS pH7.4, 50% glycerol, 0.09% sodium azide
Purification Protein G Purified
Note Detects ~24kDa.

Reference Data

Target NameHomo sapiens potassium large conductance calcium-activated channel, subfamily M, beta member 4 (KCNMB4)
Alternative Namecalcium-activated potassium channel beta 4 subunit; large conductance calcium-dependent potassium ion channel beta 4 subunit; potassium large conductance calcium-activated channel, subfamily M, beta member 4
Database LinkNP_055320
FunctionBK channels contribute to electrical impulses, proper signal transmission of information and regulation of neurotransmitter release . A gain of function mutation in the pore-forming alpha subunit of the BK channel was linked to human neurological diseases. Findings suggest that the distribution of the beta subunits in the brain can modulate the BK channels to contribute to the pathophysiology of epilepsy and dyskinesia . This has major implications on other physiological processes in tissues other than the brain.
Related Pathway

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IHC Image
IHC of BK Beta4 in brain tissues using a dilution of the antibody

 

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