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Anti-KCNJ2 Antibody EPR4530


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SKU Description Amount Price Availability*  
  • Rabbit monoclonal antibody against IRK1 / KCNJ2(clone EPR4530)
100ul 325 In Stock
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in the extracellular domain of human IRK1 / KCNJ2 was used as an immunogen.
Clone NameEPR4530 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF: 1:100 - 1:250; WB: 1:1000 - 1:10000; IHC-P: 1:250 - 1:500
Predicted MW Explanation 48 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens potassium inwardly-rectifying channel, subfamily J, member 2 (KCNJ2)
Alternative NameATFB9; HHBIRK1; HHIRK1; IRK1; KIR2.1; LQT7; SQT3
Database LinkNP_000882
Entrez Gene 3759 Human
Entrez Gene 16518 Mouse
Entrez Gene 29712 Rat
FunctionIRK1 / KCNJ2 (Inward rectifier potassium channel 2) is an inwardly rectifying K+ channel that may be blocked by divalent cations. This protein is thought to be one of multiple inwardly rectifying channels, which contribute to the cardiac inward rectifier current (IK1) (1). Thus, it probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues (2). IRK1 / KCNJ2 is associated with Smith-Magenis syndrome (1).
Related PathwayIon Channels: PotassiumTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Kir2.1 antibody [EPR4530]; All lanes : Anti-Kir2.1 antibody [EPR4530] at 1/1000 dilution.Lane 1 : 293T cell lysate.Lane 2 : A549 cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 48 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Kir2.1 antibody [EPR4530]; TA307662 at 1/250 dilution staining Kir2.1 in Human brain by Immunohistochemistry, Paraffin-embedded tissue.
IF Image
Immunocytochemistry/ Immunofluorescence - Kir2.1 antibody [EPR4530]; TA307662 at 1/100 dilution staining Kir2.1 in SH SY5Y cells by Immunofluorescence.


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