Novel HIF2A mutations disrupt oxygen sensing, leading to polycythemia, paragangliomas, and somatostatinomas Blood, Mar 2013; 121: 2563 - 2566.
[anti-HA]
Regulation of the PI3-K/Akt Survival Pathway in the Rat Endometrium Biol Reprod, Mar 2013; 88: 79.
[Akt3]
RNA elements directing in vivo assembly of the 7SK/MePCE/Larp7 transcriptional regulatory snRNP Nucleic Acids Res., Mar 2013; 10.1093/nar/gkt159.
[LA]
Ruxolitinib as potential targeted therapy for patients with JAK2 rearrangements Haematologica, Mar 2013; 98: 404 - 408.
[JAK2]
Homo sapiens potassium inwardly-rectifying channel, subfamily J, member 2 (KCNJ2)
Synonyms:
ATFB9; HHBIRK1; HHIRK1; IRK1; KIR2.1; LQT7; SQT3
Immunogen
A synthetic peptide corresponding to residues in the extracellular domain of human IRK1 / KCNJ2 was used as an immunogen.
Buffer
Store at -20 C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
IRK1 / KCNJ2 (Inward rectifier potassium channel 2) is an inwardly rectifying K+ channel that may be blocked by divalent cations. This protein is thought to be one of multiple inwardly rectifying channels, which contribute to the cardiac inward rectifier current (IK1) (1). Thus, it probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues (2). IRK1 / KCNJ2 is associated with Smith-Magenis syndrome (1).
Related Pathway
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