Home Antibody All anti-Jag1 antibodies
Also for Jag1 (NM_000214)
|Synthetic peptide surrounding amino acid 114 of rat Jagged 1|
||WB: 1-4 ug/ml
|100 µg (0.5 mg/ml) affinity purified rabbit anti- Jagged 1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.|
|Homo sapiens jagged 1 (JAG1)|
|AGS; AHD; AWS; CD339; HJ1; JAGL1|
|Jagged belongs to the DeltaSerrateLag2 (DSL) family of ligands that activate LIN12/Notch proteins. Ligands for Notch include Jagged1, Jagged2 and Delta. Jagged 1is involved in mammalian cardiovascular development and in cell-fate decisions during hematopoiesis. Mutation in Jagged1 is associated with an autosomal dominant disorder known as Alagille syndrome and Familial Tetralogy of Fallot a form of complex congenital heart disease.|
Delta-Notch Signaling Pathway
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Western blot analysis of Jagged 1 using 3T3 cell lysate.