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Home Antibody All anti-JAM2 antibodies

Anti-JAM2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308335
  • Rabbit Polyclonal antibody to JAM-B (junctional adhesion molecule 2)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402854) , 20ug Explanation
100ul 325 In Stock
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WB(2)
IHC(3)

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 1 and 294 of JAM-B (Uniprot ID#P57087)
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsIHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 33kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens junctional adhesion molecule 2 (JAM2), transcript variant 1
Alternative NameC21orf43; CD322; JAM-B; JAMB; PRO245; VE-JAM; VEJAM
Database LinkNP_067042
Entrez Gene 58494 Human
FunctionTight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs. [provided by RefSeq]
Related PathwayTransmembraneDruggable Genome Cell adhesion molecules (CAMs)Tight junctionLeukocyte transendothelial migrationEpithelial cell signaling in Helicobacter pylori infection

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
JAM-B antibody detects JAM2 protein by Western blot analysis. A. 30 ug Neuro2A whole cell lysate/extract. B. 30 ug GL261 whole cell lysate/extract. C. 30 ug C8D30 whole cell lysate/extract. D. 30 ug NIH-3T3 whole cell lysate/extract. E. 30 ug BCL-1 whole
WB Image
Sample (30 ug of whole cell lysate). A: A431 . 12 % SDS PAGE. TA308335 diluted at 1:1000
IHC Image
Immunohistochemical analysis of paraffin-embedded TOV-112D xenograft, using JAM-B(TA308335) antibody at 1:100 dilution.
IHC Image
Immunohistochemical analysis of paraffin-embedded mouse small intestine, using JAM-B(TA308335) antibody at 1:200 dilution.(Image courtesy of Koji Taniguchi, Ph.D (Laboratory of Dr. Michael Karin, UCSD.)
IHC Image
Immunohistochemical analysis of paraffin-embedded human colon, using JAM-B(TA308335) antibody at 1:200 dilution.(Image courtesy of Sergei Grivennikov Ph.D (Laboratory of Dr. Michael Karin, UCSD.)

 

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